Table of contents

The reagents used to transform epoxides, alkenes and α,β-unsaturated carbonyl compounds into allylic alcohols are considered.

Data on the synthetic methods, reactivities, biological activities and other practically important properties of 1,8-naphthyridine derivatives published over the last 15 years are analysed.

The data published during the last five years on the application of chiral derivatives of phosphorous acid in coordination chemistry and enantioselective catalysis are summarised and discussed. The effect of the nature of these ligands on the structure of metal complexes and on the efficiency of catalytic organic syntheses is shown. Hydroformylation, hydrogenation, allylic substitution and conjugate addition catalysed by transition metal complexes with optically active phosphites and hydrophosphoranes are considered. The prospects for the development of this field of research are demonstrated.

The known methods for the synthesis of 2'-functionalised nucleosides, oligonucleotides and their conjugates are systematised. The applications of 2'-modified nucleosides and oligonucleotides are discussed.