The authors discuss the possibility of obtaining the non-zero one-loop topological Casimir effect in supergravity theories and evaluate it for a number of supergravity models in the flat homogeneous Clifford-Klein spacetimes with topologies Mq=(S1)q*R4-q, q=1, 2, 3. These models are pure N=1 supergravity, N=1 supergravity coupled to matter and gauge fields, N=2 supergravity coupled to matter fields and N=8 supergravity. The results of calculations permit us to estimate the probability of the quantum birth of the Universe, possessing the effective Mq topology and filled with the fields of any of the above theories in the semiclassical approximation. In all cases it turns out that the birth of the Universe with more isotropic topology is more plausible. They also outline the perspectives of an extension of the results obtained.