Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy

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Published 7 January 2009 Europhysics Letters Association
, , Citation C. I. Smith et al 2009 EPL 85 18006 DOI 10.1209/0295-5075/85/18006

0295-5075/85/1/18006

Abstract

The analysis of single-stranded DNA attached to a polycrystalline diamond surface by reflection anisotropy spectroscopy (RAS) demonstrates that the DNA is oriented essentially vertically to the surface. RAS is able to detect the hybridisation between the attached strand and the homologous sequence.

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10.1209/0295-5075/85/18006