The motion of a quantum particle in a one-dimensional, slowly varying periodical potential is considered. By using the comparison equation method, the asymptotic expressions for exponentially small bandwidths of the low-lying energy bands is obtained. In the special case of a sinusoidal potential (corresponding to the Mathieu differential equation), the general formula reduces to an already existing result. Potentials, symmetrical and non-symmetrical, within the elementary period are discussed.