A technique, using the orthonormal basis for roots and weights of compact Lie groups, introduced by Van der Waerden and developed by Dynkin provides a convenient framework for discussing mass relations in grand unification theories. The structure constants Nalpha beta for SU(R+1), O(2R+1), Sp(2R), O(2R), and G(2) are obtained in an appendix, using an approach arising from this basis. The method for obtaining generators of non-regular subalgebras, in terms of generators of the original algebras, is discussed in terms of the basis. It is necessary to know this structure in order to trace the history of particles, originally in some grand unification group, through the various chains of decomposition into subgroups. As an illustrations, the methods are applied to finding the minimal, non-trivial, mass relations for fermions in the O(10) grand unification scheme.