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Pixelated scintillator-based compact radio thin layer chromatography scanner for radiopharmaceuticals quality control

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Published 21 November 2017 © 2017 The Author(s)
, , Citation S.J. Jeon et al 2017 JINST 12 T11003 DOI 10.1088/1748-0221/12/11/T11003

1748-0221/12/11/T11003

Abstract

We evaluated a compact and cost-effective radio thin-layer chromatography (radio-TLC) scanner for the quality control (QC) of radiopharmaceuticals. We adapted a scintillation detector, which is a Gd3Al2Ga3O12 (GAGG:Ce) scintillation crystal array coupled with a photodiode array. The performance of the scintillator array-based radio-TLC was compared with that of a commercial device. We scanned 1 μCi/μL of Tc-99m and F-18 with each device. The difference between the ROI count ratios of the developed and commercial scanners was less than 1.2%. Our scanner is sensitive enough to take measurements for a radiochemical purity test.

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10.1088/1748-0221/12/11/T11003