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Ferrum nano particles and multiwall carbon nano tubes based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

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, , Citation L Sun et al 2017 IOP Conf. Ser.: Mater. Sci. Eng. 167 012025 DOI 10.1088/1757-899X/167/1/012025

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jwang@nbic.ecnu.edu.cn

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1 School of Chemistry and Chemical Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China

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1757-899X/167/1/012025

Abstract

An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. Combined with Flow Injection Analysis (FIA) and chromatography separation column, the electrode exhibits linear response in the concentration range of 0.1 -12 μM and the sensitivity of 30.0 nA μM−1 for most of amino acids. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that the electrode is a powerful tool to investigate physiology and pathology mechanisms

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10.1088/1757-899X/167/1/012025